Detalhe da pesquisa
1.
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages.
Proc Natl Acad Sci U S A
; 120(4): e2212813120, 2023 01 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36649417
2.
Oxazole-Benzenesulfonamide Derivatives Inhibit HIV-1 Reverse Transcriptase Interaction with Cellular eEF1A and Reduce Viral Replication.
J Virol
; 93(12)2019 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30918071
3.
An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.
J Pharmacol Exp Ther
; 360(1): 140-151, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-27827303
4.
Europium-Labeled Synthetic C3a Protein as a Novel Fluorescent Probe for Human Complement C3a Receptor.
Bioconjug Chem
; 28(6): 1669-1676, 2017 06 21.
Artigo
Inglês
| MEDLINE | ID: mdl-28562031
5.
Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis.
J Pharmacol Exp Ther
; 356(2): 387-96, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26660228
6.
Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity.
Bioorg Med Chem Lett
; 26(3): 986-991, 2016 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26725028
7.
Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages.
Antimicrob Agents Chemother
; 60(3): 1521-9, 2015 Dec 28.
Artigo
Inglês
| MEDLINE | ID: mdl-26711769
8.
Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships.
Bioorg Med Chem Lett
; 25(23): 5604-8, 2015 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26522948
9.
Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages.
J Biol Chem
; 288(35): 25362-25374, 2013 Aug 30.
Artigo
Inglês
| MEDLINE | ID: mdl-23853092
10.
Stereoelectronic effects dictate molecular conformation and biological function of heterocyclic amides.
J Am Chem Soc
; 136(34): 11914-7, 2014 Aug 27.
Artigo
Inglês
| MEDLINE | ID: mdl-25102224
11.
C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling.
FASEB J
; 27(2): 822-31, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23118029
12.
Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages.
J Innate Immun
; 15(1): 468-484, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36882040
13.
The histone deacetylase Hdac7 supports LPS-inducible glycolysis and Il-1ß production in murine macrophages via distinct mechanisms.
J Leukoc Biol
; 111(2): 327-336, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34811804
14.
QSAR Classification Models for Prediction of Hydroxamate Histone Deacetylase Inhibitor Activity against Malaria Parasites.
ACS Infect Dis
; 8(1): 106-117, 2022 01 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34985259
15.
Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1-3 in mesendoderm cell differentiation.
Cell Rep
; 39(7): 110818, 2022 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35584683
16.
Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats.
J Cardiovasc Pharmacol
; 58(5): 479-86, 2011 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-21753735
17.
Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice.
Int J Parasitol Drugs Drug Resist
; 17: 118-127, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34560571
18.
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates.
J Med Chem
; 64(4): 2186-2204, 2021 02 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33570940
19.
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv
; 7(49): eabg4007, 2021 Dec 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34851660
20.
Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components.
Bioorg Med Chem Lett
; 20(23): 7080-4, 2010 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20951583